Unexplained loss of muscle mass, also known as cachexia, can be concerning and frustrating. It is characterized by the unintentional and abnormal loss of lean muscle and body mass that cannot be reversed through conventional nutrition techniques. While some muscle loss is normal with aging, unexplained wasting and weakness warrants medical evaluation.
There are many potential causes of cachexia. These include:
- Chronic or uncontrolled diseases: Cachexia can stem from illnesses like cancer, kidney disease, congestive heart failure, COPD, cystic fibrosis, dementia, AIDS, tuberculosis, and more. The inflammation and metabolism changes from illness can accelerate muscle breakdown.
- Hormone or endocrine imbalances: Low levels of anabolic hormones like testosterone, estrogen, growth hormone, IGF-1, and insulin can lead to muscle wasting. High cortisol from chronic stress can also break down lean tissue. Getting comprehensive hormone testing is wise.
- Nutrient deficiencies: Lacking key amino acids, protein, calories, iron, vitamin D, zinc or other nutrients can impair muscle maintenance over time.
- Medications: Certain prescription drugs like steroids, chemotherapy, anticonvulsants, opioids, and others list muscle loss as a potential side effect.
- Immobility or low physical activity: Sedentary living and bed rest diminish crucial muscle stimulation needed to maintain mass. Strength training is protective.
If you suffer persistent,
progressive loss of muscle mass and strength without clear cause, I recommend getting evaluated by a doctor. Underlying illness or imbalances may be uncovered with
blood tests, body composition scans, endoscopy or other diagnostics.
Once any underlying condition is treated,
anabolic therapies can help regain strength and lean tissue:
- Nutrition counseling with higher protein, calories, leucine, HMB, creatine
- Hormone replacement at Renewal Hormone Clinic if levels are low
- Exercise programs with strength training and cardio activity
- Medications like oxandrolone, megestrol acetate, or others
Regaining muscle mass takes consistent effort but is worthwhile to restore strength, function and metabolic health. Reach out anytime if you would like personalized guidance. Wishing you the best of health!